Mouthwashing, the doomed-freighter horror hit, is getting a live-action film
Wrong Organ's indie horror game Mouthwashing will become a feature film directed by Karyn Kusama, with Screen Gems and Scott Derrickson attached.
Edited by Dot Matrix, Editor-in-Chief

Specimen of the week: a freight ship called the Tulpar, adrift and off course, with five crew members slowly coming apart inside it. That is Mouthwashing, the indie horror game from Wrong Organ, published by Critical Reflex, and it is now headed for the big screen. Wrong Organ and Sony Pictures’ Screen Gems announced the film on Thursday, October 29.1
The facts: Mouthwashing is a horror game that first came out on PC on September 26, 2024, and it is on consoles as of October 29. IGN gave it a 9 out of 10.1 The sources do not state a price or the size of the studio.
What sets it apart is its pressure-cooker premise. When the Tulpar leaves its course, the crew of the Pony Express freighter has to cope with starvation, isolation, paranoia and hallucinations, and even defend themselves from each other.1 Horror where the threat is partly the people sharing your hallway is a hard thing to adapt, so the choice of director matters.
Karyn Kusama, known for Jennifer’s Body and Yellowjackets, is set to direct. Matt Manfredi and Phil Hay, who wrote The Invitation, are writing the script. Scott Derrickson (Doctor Strange, The Black Phone) produces with C. Robert Cargill and Vince Cheng under their Crooked Highway banner.1 Plot details are unconfirmed, and no cast has been named.1
Field note: some of the game’s characters were directly inspired by real-life actors, Shelley Duvall among them, so the casting guessing game writes itself.1
The announcement follows more than two weeks of rumors in the game’s fanbase about a movie.1 It also lands as games keep heading to screens: a PUBG live-action show at Netflix, a Battlefield film, a Street Fighter movie that opened earlier this month, and a Resident Evil film from Zach Cregger.1
Who is it for? Horror fans who like their dread claustrophobic and character-driven, and anyone who wants to play it before the movie shapes how everyone talks about it.
Our read: A small team’s ship-bound nightmare getting a director with Kusama’s horror track record is the kind of pairing that could work, because the game’s strength is its people, not its monsters. The real test is whether the film keeps that crew-against-crew dread intact.
Worth knowing: Mouthwashing is available on PC and, as of October 29, consoles. The sources give no store page or price.
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